Angioimmunoblastic T‐cell lymphoma after acute myeloid leukemia: Alleged common pathogenesis. A case report and literature review | Zendy

Iturrate Isabel | Zendy; Loscertales Javier | Zendy; FernándezRuiz Elena | Zendy; Muñoz Patricia | Zendy; López Consuelo | Zendy; del Campo Luciana | Zendy; Muñoz Cecilia | Zendy; Alegre Adrián | Zendy

Open Access

Angioimmunoblastic T‐cell lymphoma after acute myeloid leukemia: Alleged common pathogenesis. A case report and literature review

Author(s) -

Iturrate Isabel,

Loscertales Javier,

FernándezRuiz Elena,

Muñoz Patricia,

López Consuelo,

del Campo Luciana,

Muñoz Cecilia,

Alegre Adrián

Publication year - 2020

Publication title -

clinical case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.21

H-Index - 9

ISSN - 2050-0904

DOI - 10.1002/ccr3.3430

Subject(s) - medicine , myeloid leukemia , angioimmunoblastic t cell lymphoma , epigenetics , pathogenesis , myeloid , lymphoma , cancer research , mutation , gene , immunology , genetics , biology , t cell , immune system

The genomic landscape of AITL is characterized by mutation of epigenetic modifiers. This gene expression pattern resembles myeloid diseases and shows a potential role for hypomethylating agents as possible therapy for AITL.

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