Open AccessAngioimmunoblastic T‐cell lymphoma after acute myeloid leukemia: Alleged common pathogenesis. A case report and literature review
Author(s) -
Iturrate Isabel,
Loscertales Javier,
FernándezRuiz Elena,
Muñoz Patricia,
López Consuelo,
del Campo Luciana,
Muñoz Cecilia,
Alegre Adrián
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.3430
Subject(s) - medicine , myeloid leukemia , angioimmunoblastic t cell lymphoma , epigenetics , pathogenesis , myeloid , lymphoma , cancer research , mutation , gene , immunology , genetics , biology , t cell , immune system
The genomic landscape of AITL is characterized by mutation of epigenetic modifiers. This gene expression pattern resembles myeloid diseases and shows a potential role for hypomethylating agents as possible therapy for AITL.