Open AccessLight chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance
Author(s) -
Okawara Sayoko,
Bando Kenichiro,
Tsukada Junichi
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.3362
Subject(s) - medicine , immunoglobulin light chain , multiple myeloma , bortezomib , bone marrow , monoclonal gammopathy of undetermined significance , monoclonal gammopathy , pathology , plasma cell , monoclonal , clinical significance , paraproteinemias , monoclonal antibody , antibody , immunology
Rod‐like inclusions have rarely been described in cases of monoclonal gammopathy of renal significance or multiple myeloma. The key finding in our case is the strong κ‐light chain positivity of rod‐like inclusions in plasma cells, which confirms their immunoglobulin nature. Therapeutic benefit of bortezomib was also observed.