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Germline and somatic genetic alterations in two first‐degree relatives with appendiceal low‐grade mucinous carcinoma peritonei
Author(s) -
King Mary Caitlin,
MunozZuluaga Carlos,
Ledakis Panayotis,
Studeman Kimberley,
Sittig Michelle,
Gushchin Vadim,
Sardi Armando
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.3338
Subject(s) - pseudomyxoma peritonei , medicine , appendix , mucinous carcinoma , germline mutation , somatic cell , pathology , adenocarcinoma , oncology , mutation , cancer , genetics , gene , biology , paleontology
Comparing genetic mutations of first‐degree relatives with appendiceal pseudomyxoma peritonei may explain clinical outcomes and disease pathogenesis. Molecular profiling of mucinous tumors may identify improved treatments to traditional chemotherapy.

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