Open AccessMutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations
Author(s) -
Nasirnejad Sola Farzaneh,
Morovvati Saeid,
Sabetghadam Moghadam Mitra,
Entezari Malihe
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.3294
Subject(s) - medicine , mutation , gene mutation , gene , genetics , biology
This investigation facilitates a better understanding of inhibitor development, the critical treatment morbidity in HA patients. Furthermore, six novel mutations are reported, which would expand the mutation spectrum of the F8 gene.