Open AccessPhenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related
Author(s) -
Kutasovic Jamie R.,
McCart Reed Amy E.,
Sokolova Anna,
Jayanthan Janani,
Da Silva Leonard,
Simpson Peter T.,
Lakhani Sunil R.
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.3257
Subject(s) - medicine , pathology , metastasis , cancer , metastatic breast cancer , breast cancer , invasive lobular carcinoma , stomach , oncology , invasive ductal carcinoma
Breast cancer metastasis to the stomach is rare; invasive lobular carcinoma has a predilection to spread to the gastrointestinal system and is morphologically similar to primary diffuse gastric carcinoma. This case highlights heterogeneous metastatic progression and that documentation of heterogeneity is important for informing future treatment strategies and prognostication.