Open AccessLisch nodules and iris mammillations in two siblings with familial legius syndrome
Author(s) -
Bixel Kaitlyn D.,
Cano Miguel J.,
Johnson Damon M.,
Gomez Benjamin,
Lobsinger Laura V.,
Valentin Frank E.,
Hsieh David T.,
Rohena Luis O.
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2861
Subject(s) - intertriginous , medicine , iris (biosensor) , neurofibromatosis , dermatology , penetrance , pediatrics , pathology , phenotype , genetics , disease , biology , gene , computer security , computer science , biometrics
Legius syndrome is characterized by numerous café‐au‐lait macules and intertriginous freckling, but typically lacks the distinctive tumor manifestations of neurofibromatosis type 1. We report two siblings with Legius syndrome and Lisch nodules illustrating the importance of eye surveillance in these patients.