Open AccessAntenatal diagnosis of absence of septum pellucidum
Author(s) -
Ben M'Barek Imane,
Tassin Mikael,
Guët Agnes,
Simon Isabelle,
Mairovitz Valerie,
Mandelbrot Laurent,
Picone Olivier
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2666
Subject(s) - septum pellucidum , medicine , dysplasia , prenatal diagnosis , pediatrics , anatomy , pregnancy , pathology , fetus , genetics , biology
The absence of septum pellucidum (ASP) is a rare disease, which affects the structure of the brain. It is either isolated or associated with various congenital brain malformations. The diagnosis of ASP can be performed by second‐trimester ultrasound. When the ASP is isolated, prenatal counseling is optimistic regarding neurological outcome, but there is a 20% risk of septo‐optic dysplasia in the neonate.