Open AccessCADASIL presenting as late‐onset mania with anosognosia
Author(s) -
Uppal Manik,
Kanellopoulos Dora,
Kotbi Nabil
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2594
Subject(s) - cadasil , leukoencephalopathy , anosognosia , medicine , mania , neuropsychology , personality changes , psychiatry , pediatrics , bipolar disorder , magnetic resonance imaging , pathology , radiology , cognition , disease
The diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) should be considered in patients with late‐onset personality change and mania. However, neuropsychological deficits precipitated by the disorder pose significant challenges to recognition and appropriate management of CADASIL in susceptible patients.