Open AccessThe sublingual use of atropine in the treatment of clozapine‐induced sialorrhea: A systematic review
Author(s) -
Van der Poorten Thomas,
De Hert Marc
Publication year - 2019
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2431
Subject(s) - sialorrhea , clozapine , medicine , atropine , schizophrenia (object oriented programming) , anesthesia , dermatology , psychiatry
Clozapine is considered the golden standard in the treatment of therapy‐resistant schizophrenia; however, it associated with bothersome side effects such as sialorrhea. Current evidence suggests that the sublingual use of atropine seems to be safe and effective and could be considered as a first‐line treatment of clozapine‐induced sialorrhea.