Open AccessMultiple myeloma with clivus involvement, neurological symptoms, and 45 g/L proteinorachia
Author(s) -
Chantran Yannick,
Lavillegrand JeanRémi,
Lefrere Bertrand,
Gaillet Antoine,
Aucouturier Pierre,
Garderet Laurent
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2404
Subject(s) - clivus , medicine , multiple myeloma , cerebrospinal fluid , intrathecal , pathology , surgery , skull
The mechanical obstruction of cerebrospinal fluid (CSF) flow can lead to very high hyperproteinorachia. In myeloma, tumoral clivus obstruction can cause such high proteinorachia, associated with paraprotein detection in the CSF in absence of intrathecal synthesis.