Open AccessHomozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention
Author(s) -
Yasu Takanori,
Shimoyama Masahiro,
Wada Hiroshi,
Iwakura Tomohiro,
Toyoda Shigeru,
Kawabe Atsuhiko,
Sugiyama Takushi
Publication year - 2019
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2299
Subject(s) - medicine , percutaneous coronary intervention , cardiology , ldl apheresis , apheresis , familial hypercholesterolemia , coronary artery disease , artery , lipoprotein , stenosis , cholesterol , myocardial infarction , platelet
We successfully treated a patient with homozygous familial hypercholesterolemia (HoFH) with stable coronary arterial disease using optimal medical therapy and low‐density lipoprotein (LDL) apheresis for 16 years without percutaneous coronary intervention or bypass surgery. Intensive LDL lowering using apheresis and medication protected the patient from coronary atherosclerotic progression even in HoFH.