Open AccessLysozyme nephropathy in chronic myelomonocytic leukemia
Author(s) -
Patel Ami B.,
Miles Rodney R.,
Deininger Michael W.
Publication year - 2019
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2188
Subject(s) - medicine , lysozyme , chronic myelomonocytic leukemia , nephropathy , immunology , cancer research , biochemistry , endocrinology , bone marrow , myelodysplastic syndromes , biology , diabetes mellitus
Lysozyme nephropathy is a frequently unrecognized cause of renal disease in chronic myelomonocytic leukemia and may serve as a novel indication for treatment in this patient population. We demonstrate that in newly diagnosed CMML patients, plasma lysozyme levels are positively correlated with both absolute monocyte count and serum creatinine.