Use of low dose of rFVIIa (recombinant Factor VII activated) to control late bleeding after percutaneous dilational tracheostomy | Zendy

Nicosia Dario | Zendy; Federico Antonino | Zendy; Vigna Ivan | Zendy; Iozzo Pasquale | Zendy; Misseri Giovanni | Zendy; Cortegiani Andrea | Zendy

Open Access

Use of low dose of rFVIIa (recombinant Factor VII activated) to control late bleeding after percutaneous dilational tracheostomy

Author(s) -

Nicosia Dario,

Federico Antonino,

Vigna Ivan,

Iozzo Pasquale,

Misseri Giovanni,

Cortegiani Andrea

Publication year - 2019

Publication title -

clinical case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.21

H-Index - 9

ISSN - 2050-0904

DOI - 10.1002/ccr3.2061

Subject(s) - medicine , bolus (digestion) , anesthesia , intravenous bolus , recombinant factor viia , percutaneous , surgery , recombinant dna , factor viia , coagulation , biochemistry , chemistry , tissue factor , gene

Key Clinical Message In our case, the use of a low intravenous bolus dose of rFVIIa (recombinant factor VII activated; 15‐20 mcg/kg) was effective and uneventful in controlling late postprocedural PDT bleeding associated with thrombocytopenia that cannot be corrected and after all other treatments failed.

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