Open AccessToll‐like receptor 4 promoter polymorphisms in a familial mediterranean fever patient with asymptomatic bacteriuria
Author(s) -
Kawamoto Shinichiro,
Masutani Ryota,
Kurata Keiji,
Shima Etsuko,
Iwatani Yoshinori,
Takubo Takayuki
Publication year - 2019
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1941
Subject(s) - familial mediterranean fever , medicine , mefv , asymptomatic , pyrin domain , asymptomatic bacteriuria , immunology , pathophysiology , q fever , pathogen , toll like receptor , inflammation , genetics , gene , bacteriuria , mutation , inflammasome , gene mutation , innate immune system , disease , biology , immune system , urinary system
Key Clinical Message A periodic fever, due to inherited inflammatory disorders, can be misdiagnosed as a common infection, when a possible pathogen is detected from a patient. TLR4 SNPs that are responsible for asymptomatic bacteriuria might disturb the pathophysiology of familial Mediterranean fever without MEFV mutations.