Open AccessMembranous or membranous‐like GN: A case report of massive proteinuria, positive serum with negative PLA2R on biopsy
Author(s) -
Kaur Gurwant,
Chen Guoli
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1849
Subject(s) - medicine , proteinuria , pathology , renal biopsy , stain , biopsy , membranous nephropathy , antibody , glomerulonephritis , immunofluorescence , nephrotic syndrome , gastroenterology , staining , immunology , kidney
Key Clinical Message This case report represents primary membranous glomerulonephritis (MGN) with positive serum anti‐PLA2R antibodies, 2+ positivity for IgG4 on immunofluorescence with routine fresh‐frozen sections and negative PLA2R stain on biopsy. He was treated as primary MGN based on positive serum PLA2R and the absence of clinical symptoms or signs suggestive of any secondary MGN.