Open AccessLithium improved behavioral and epileptic symptoms in an adolescent with ring chromosome 20 and bipolar disorder not otherwise specified
Author(s) -
Inal Adlane,
Chaumette Boris,
Soleimani Maryam,
Guerrot AnneMarie,
Goldenberg Alice,
Lebas Axel,
Gerardin Priscille,
Ferrafiat Vladimir
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1796
Subject(s) - lithium (medication) , medicine , bipolar disorder , phenotype , girl , psychiatry , pediatrics , bioinformatics , genetics , biology , gene
Key Clinical Message We present a case of ring chromosome 20 syndrome in a twelve‐year‐old girl, with resistant epileptic disease and severe behavioral impairment that both drastically improved after a lithium challenge. If replicated, this could support the use of lithium as a safe treatment in the management of this severe phenotype.