Open AccessDNM1 Mutation in a child associated with progressive bilateral mesial temporal sclerosis
Author(s) -
Lazzara Alexandra,
Asghar Sheila,
Zacharia Thomas,
Byler Debra
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1793
Subject(s) - medicine , status epilepticus , mutation , epilepsy , mesial temporal lobe epilepsy , hippocampal sclerosis , gene , genetics , psychiatry , temporal lobe , biology
Key Clinical Message This case represents a novel association of a DNM1 gene mutation with status epilepticus and progressive bilateral mesial temporal sclerosis. This could have future implications for treatment in patients with DNM1 mutation and refractory epilepsy as the mesial temporal sclerosis may become bilateral, making the patient a poor surgical candidate.