Open AccessThe use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog
Author(s) -
Bellis Tara J.,
Gibeon Laura
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1733
Subject(s) - lamotrigine , medicine , cardiotoxicity , ingestion , refractory (planetary science) , anesthesia , pharmacology , chemotherapy , epilepsy , psychiatry , physics , astrobiology
Key Clinical Message Lamotrigine is a sodium and calcium channel blocker, used to treat seizures in people. Dogs metabolize Lamotrigine to a cardiotoxic metabolite that causes severe, often fatal ventricular arrhythmias. This report documents the successful treatment of refractory Lamotrigine cardiotoxicity in a dog, using intralipid emulsion therapy.