Open AccessMetabolic acidosis after sodium thiosulfate infusion and the role of hydrogen sulfide
Author(s) -
Hunt Guenola M.,
Ryder Hilary F.
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1673
Subject(s) - medicine , sodium thiosulfate , metabolic acidosis , acidosis , hydrogen sulfide , asymptomatic , sulfur , inorganic chemistry , chemistry , organic chemistry
Key Clinical Message Sodium thiosulfate (STS), first‐line treatment for calcific uremic arteriolopathy, causes a mild asymptomatic acidosis in many patients. However, severe, life‐threatening acidosis out of proportion with the expected acid load of STS may occur, potentially due to metabolism of STS to hydrogen sulfide.