Florid dermatopathic lymphadenopathy—A morphological mimic of Langerhans cell histiocytosis | Zendy

Ravindran Aishwarya | Zendy; Goyal Gaurav | Zendy; Failing Jarrett J. | Zendy; Go Ronald S. | Zendy; Rech Karen L. | Zendy

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Florid dermatopathic lymphadenopathy—A morphological mimic of Langerhans cell histiocytosis

Author(s) -

Ravindran Aishwarya,

Goyal Gaurav,

Failing Jarrett J.,

Go Ronald S.,

Rech Karen L.

Publication year - 2018

Publication title -

clinical case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.21

H-Index - 9

ISSN - 2050-0904

DOI - 10.1002/ccr3.1663

Subject(s) - medicine , langerhans cell histiocytosis , histiocytosis , pathology , dermatology , lymphatic disease , cervical lymphadenopathy , disease

Key Clinical Message The histopathology of reactive florid dermatopathic lymphadenopathy shows overlap with Langerhans cell histiocytosis ( LCH ) involving the lymph node, which may lead to misdiagnosis. These entities can be distinguished by recognition of the sinus‐based distribution of Langerhans cells in LCH , in contrast to the paracortical distribution of Langerhans cells, pigment‐laden histiocytes, and small lymphocytes in dermatopathic lymphadenopathy.

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