Open AccessFlorid dermatopathic lymphadenopathy—A morphological mimic of Langerhans cell histiocytosis
Author(s) -
Ravindran Aishwarya,
Goyal Gaurav,
Failing Jarrett J.,
Go Ronald S.,
Rech Karen L.
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1663
Subject(s) - medicine , langerhans cell histiocytosis , histiocytosis , pathology , dermatology , lymphatic disease , cervical lymphadenopathy , disease
Key Clinical Message The histopathology of reactive florid dermatopathic lymphadenopathy shows overlap with Langerhans cell histiocytosis ( LCH ) involving the lymph node, which may lead to misdiagnosis. These entities can be distinguished by recognition of the sinus‐based distribution of Langerhans cells in LCH , in contrast to the paracortical distribution of Langerhans cells, pigment‐laden histiocytes, and small lymphocytes in dermatopathic lymphadenopathy.