Open AccessCyclic thrombocytopenia with statistically significant neutrophil oscillations
Author(s) -
Langlois Gabriel P.,
Arnold Donald M.,
Potts Jayson,
Leber Brian,
Dale David C.,
Mackey Michael C.
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1611
Subject(s) - immune thrombocytopenia , medicine , clinical significance , platelet , statistical significance , immune system , statistical analysis , immunology , cardiology , gastroenterology , statistics , mathematics
Key Clinical Message Cyclic thrombocytopenia is often misdiagnosed as immune thrombocytopenia due to similar clinical features, a fact of significance because cyclic thrombocytopenia generally responds poorly to treatments used successfully in immune thrombocytopenia. A precise diagnosis must establish the statistical significance of periodicity of the platelet counts using statistical methods (eg, Lomb‐Scargle periodogram).