Open AccessApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes
Author(s) -
Keefe Christel,
Lawson Sarah
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1584
Subject(s) - medicine , hypertriglyceridemia , type 2 diabetes , diabetes mellitus , apolipoprotein e , endocrinology , disease , triglyceride , cholesterol
Key Clinical Message We report a case of pediatric diabetic ketoacidosis (DKA) with significant hypertriglyceridemia. The patient was found to have the e3/ e4 isoform of ApoE, increasing risk of hypertriglyceridemia in DKA. We suggest further genetic investigation for patients presenting with severe hypertriglyceridemia and DKA.