Open AccessSevere allograft rejection in an intestinal transplant patient following oral immunoglobulin treatment for chronic norovirus infection: a case report
Author(s) -
Åberg Fredrik,
Savikko Johanna,
Anttila VeliJukka,
Mäkisalo Heikki
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1493
Subject(s) - medicine , tacrolimus , norovirus , immunosuppression , antibody , immunology , immunoglobulin g , transplantation , virus
Key Clinical Message In an intestinal transplant patient under triple immunosuppression therapy with tacrolimus levels >10 ng/L, a 2‐day oral immunoglobulin therapy given as treatment for chronic norovirus infection was temporally closely associated with the development of severe steroid‐resistant acute graft rejection, thus suggesting that oral immunoglobulin might be able to promote a rejection response.