Open AccessLarge granular lymphocytic leukemia complicating autoimmune polyglandular syndrome type 1 in siblings
Author(s) -
Harrison Jonathan S.,
Parmar Harsh,
Wang Xiangbing D.
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1454
Subject(s) - medicine , dermatology , leukemia , immunology
Key Clinical Message Autoimmune polyglandular syndrome type 1 (APS1) is a rare autosomal recessive disorder, and large granular lymphocytic leukemia (LGLL) may, even more rarely, complicate APS1. LGLL may be subtle in presentation, but it is imperative to recognize LGLL in APS1 promptly, as outcome may otherwise be fatal, as described herein.