Open AccessSevere pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids
Author(s) -
Liatsos George D.,
Tsironi Ioanna,
Vassilopoulos Dimitrios,
Dourakis Spyridon
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1396
Subject(s) - pancytopenia , medicine , felty's syndrome , prednisone , neutropenia , blood count , dermatology , surgery , chemotherapy , bone marrow
Key Clinical Message In severe cases of pancytopenia with subsequent infections due to long‐term untreated Felty's syndrome, the initiation of immunosuppressive treatment with sole prednisone (1 mg/kg iv ) should be considered, despite that, the low neutrocytes count would make one physician hesitant. A full resolution of whole blood count within 3 weeks and a 30% reduction in spleens sized was noted.