Open AccessUnexpected disseminated histoplasmosis detected by bone marrow biopsy in a solid organ transplant patient
Author(s) -
Simon Caroline T.,
MurgaZamalloa Carlos A.,
Bachman Michael A.,
Petty Lindsay A.,
Choi Sarah M.
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1282
Subject(s) - medicine , histoplasmosis , immunosuppression , bone marrow transplant , hemophagocytic lymphohistiocytosis , biopsy , solid organ , bone marrow , pathology , intensive care medicine , organ transplantation , bone marrow transplantation , transplantation , surgery , immunology , disease
Key Clinical Message Disseminated histoplasmosis and hemophagocytic lymphohistiocytosis show overlapping features, which require careful contextual interpretation. Histopathologic evaluation can potentially rapidly identify cases of possible histoplasmosis. A high index of clinical suspicion, particularly in endemic areas and in a setting of immunosuppression, is critical to appropriate diagnosis and treatment.