Open AccessLeukemic phase and CSF involvement of diffuse large B‐cell lymphoma with a complex karyotype including a TP 53 deletion
Author(s) -
Sinkoff Jillian,
Olteanu Horatiu,
Peterson Jess F.,
Shah Nirav N.
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1250
Subject(s) - immunophenotyping , karyotype , medicine , lymphoma , diffuse large b cell lymphoma , b cell , pathology , cancer research , immunology , flow cytometry , antibody , gene , chromosome , biology , genetics
Key Clinical Message Diffuse large B‐cell lymphoma in rare instances can present initially in a leukemic phase and mimic other lymphoid diseases. In such cases, advanced diagnostic testing including immunophenotyping, FISH analysis, and karyotyping can help determine the accurate diagnosis which is key in the management of the disease.