Open AccessMultiple large osteolytic lesions in a patient with systemic mastocytosis: a challenging diagnosis
Author(s) -
Bonifacio Massimiliano,
Zanotti Roberta,
Guardalben Emanuele,
Mimiola Elda,
Scognamiglio Francesca,
Perbellini Omar,
De Matteis Giovanna,
Escribano Luis,
Bonadonna Patrizia,
Grigolato Daniela,
Bissoli Sergio,
Parisi Alice,
Zamò Alberto,
Ambrosetti Achille,
Rossini Maurizio
Publication year - 2017
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1232
Subject(s) - systemic mastocytosis , medicine , pathology , dermatology , bone marrow
Key Clinical Message Patients with advanced variants of Systemic Mastocytosis may develop destructive bone lesions when massive mast cell ( MC ) infiltrates are present. Finding of large osteolyses in indolent systemic mastocytosis, typically characterized by low MC burden, should prompt investigations for an alternative explanation.