Open AccessAllogeneic hematopoietic cell transplantation in an adult patient with Glanzmann thrombasthenia
Author(s) -
Cid Ana R.,
Montesinos Pau,
SánchezGuiu Isabel,
Haya Saturnino,
Lorenzo Jose I.,
Sanz Jaime,
Moscardo Federico,
Puig Nieves,
Planelles Dolores,
Bonanad Santiago,
Sanz Guillermo F.,
Vicente Vicente,
GonzálezManchón Consuelo,
Lozano María L.,
Rivera José,
Sanz Miguel A.
Publication year - 2017
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1206
Subject(s) - medicine , glanzmann's thrombasthenia , thrombasthenia , hematopoietic stem cell transplantation , transplantation , refractory (planetary science) , hematopoietic cell , haematopoiesis , stem cell , platelet , immunology , surgery , platelet aggregation , biology , genetics , physics , astrobiology
Key Clinical Message Glanzmann thrombasthenia is a rare bleeding disorder that can present life‐threatening bleeding. Our patients develop antiplatelet antibodies that become refractory to any pharmacological treatment. Allogeneic hematopoietic stem‐cell transplantation is the only currently curative procedure, but has major risks mainly in adult; indeed, our patient died.