Open AccessAcromegaly and Cushing's syndrome caused by a neuroendocrine tumor arising within a sacrococcygeal teratoma
Author(s) -
Babiker Tarig,
Kyrodimou Efstathia,
Berney Daniel M.,
Gurnell Mark,
Drake William M.,
Brooke Antonia
Publication year - 2017
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1148
Subject(s) - medicine , acromegaly , sacrococcygeal teratoma , neuroendocrine tumors , endocrinology , growth hormone , hormone , pregnancy , fetus , biology , genetics
Key Clinical Message A 60‐year‐old man with a pre‐existing stable sacrococcygeal teratoma developed acromegaly, ectopic Cushing's syndrome, and 5 HIAA secretion. To our knowledge, this represents the first reported case of ACTH and serotonin secretion, and likely GHRH or GH cosecretion, from a sacrococcygeal teratoma in an adult.