Open AccessA case of penta X syndrome caused by nondisjunction in maternal meiosis 1 and 2
Author(s) -
Markholt Sara,
Graakjaer Jesper,
Thim Signe Bødker,
Høst Bente,
Skytte AnneBine
Publication year - 2017
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1004
Subject(s) - nondisjunction , meiosis , medicine , pregnancy , phenotype , x chromosome , down syndrome , genetics , gynecology , aneuploidy , chromosome , biology , psychiatry , gene
Key Clinical Message The prenatal abnormalities in patients with penta X syndrome appear late in pregnancy and are nonspecific. In contrast, the postnatal phenotype is well described although new findings are still revealed. Penta X syndrome is a result of successive nondisjunctions of the X chromosomes in both maternal meiotic divisions.