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Transcatheter aortic valve implantation for degenerated aortic valves: Experience with a new supra‐annular device. The Spanish Allegra valve‐in‐valve (SAVIV) registry
Author(s) -
Moreno Raúl,
Baz JoséAntonio,
Moreu José,
Berenguer Alberto,
GonzálvezGarcía Ariana,
Galeote Guillermo,
Hernández Ubaldo,
Cantón Tomás,
JiménezValero Santiago,
JuradoRomán Alfonso,
Moya Halley,
Lázaro Esther
Publication year - 2021
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.29742
Subject(s) - medicine , aortic valve , hemodynamics , regurgitation (circulation) , stenosis , catheter , aortic valve replacement , surgery , aortic valve stenosis , cardiology
Abstract Objectives The objective was to evaluate the results of valve‐in‐valve procedures performed with the Allegra device. Background Transcatheter aortic valve implantation to treat degenerated biological aortic valves (valve‐in‐valve) is an established procedure in most catheterization laboratories, but the results are poorer than procedures done in native aortic stenosis. The Allegra device (Biosensors, Morges, Switzerland) has an excellent design to treat these patients. Methods All patients with severely degenerated biological aortic valve treated with the Allegra device in centers from Spain until December 2020 were included ( n  = 29). Hemodynamic results and 30‐day clinical outcomes were evaluated. The predominant hemodynamic failure was stenosis in 15, regurgitation in 11, and a combination of both in 3 cases. Time from aortic valve replacement to valve‐in‐valve procedure was 8.4 ± 3.9 years (range 3.3–22.1). Results After the procedure, maximum and mean trans‐valvular gradients were 17.4 ± 12.3 and 8.4 ± 6.1 mmHg, respectively. Device success was obtained in 28 patients (96.6%). In one patient with a degenerated 19 mm prosthetic valve, mean gradient after the procedure was 22 mmHg. No patients had a para‐valvular leak grade >1. There were no deaths during the hospitalization or at 30 days and one patient suffered a stroke. Conclusions The Allegra trans‐catheter aortic valve offers optimal hemodynamic results in patients with severely degenerated biological aortic valve.

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