Premium
GRACEfully assessing the timeline for noninfarct‐related artery intervention in ST‐elevation myocardial infarction patients
Author(s) -
Shah Jay,
Levy Michael S.
Publication year - 2021
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.29719
Subject(s) - medicine , cardiogenic shock , conventional pci , myocardial infarction , percutaneous coronary intervention , culprit , cardiology , randomized controlled trial , coronary artery disease , artery , intervention (counseling) , psychiatry
Key Points A large registry study of ST‐elevation myocardial infarction (STEMI) patients with multivessel disease and without cardiogenic shock demonstrated that staged in‐hospital intervention of the noninfarct‐related artery was associated with a reduced risk of all‐cause mortality when compared to culprit‐only PCI or immediate multivessel intervention. A subgroup analysis stratified by the Global Registry of Acute Coronary Events (GRACE) score, showed a mortality benefit in high‐risk patients (GRACE score > 140) undergoing staged in‐hospital intervention of the noninfarct‐related artery with a median interval between the two procedures of 5 days. Further large, randomized trials are needed to help clarify appropriate timing for nonculprit staged intervention in STEMI patients.