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Paravalvular leak after TAVR: remarkable improvement but not the time to shift focus
Author(s) -
Mahtta Dhruv,
Jneid Hani
Publication year - 2021
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.29666
Subject(s) - medicine , valve replacement , incidence (geometry) , cardiology , leak , surgery , stenosis , physics , environmental engineering , optics , engineering
Key Points Significant paravalvular leak (PVL) among patients undergoing transcatheter aortic valve replacement (TAVR) portends a poor prognosis and is often associated with increased mortality. TAVR with the latest generation balloon‐expandable valve platform, Edwards SAPIEN 3 Ultra, is associated with lower incidence of PVL (including lower rates of mild PVL and zero incidence of moderate and severe PVL) compared to its predecessor, the SAPIEN 3 valve platform. The similar safety profile, comparable deliverability, and lower PVL observed with the Edwards SAPIEN 3 Ultra system will likely lead to its increased adoption in clinical practice. Future studies are needed to examine its long‐term clinical outcomes and further decipher the procedural and patient factors associated with PVL.