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The challenges of coronary no‐reflow phenomenon
Author(s) -
Case Brian C.,
Satler Lowell F.
Publication year - 2021
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.29571
Subject(s) - medicine , no reflow phenomenon , percutaneous coronary intervention , cardiology , epinephrine , myocardial infarction , randomized controlled trial , refractory (planetary science) , physics , astrobiology
Key Points Proof‐of‐concept study demonstrates that intracoronary epinephrine could provide substantial improvement in coronary flow in ST‐elevation myocardial infarction refractory coronary no‐reflow during primary percutaneous coronary intervention. Intracoronary epinephrine is a potential solution to an uncommon but clinically serious phenomenon with limited, if any, therapeutic alternatives. A prospective, large, randomized trial, which is powered for clinical events, would help further validate this management technique.