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Predictors of short‐ and long‐term outcomes of patients undergoing transcatheter mitral valve edge‐to‐edge repair
Author(s) -
Geyer Martin,
Keller Karsten,
Born Sonja,
Bachmann Kevin,
Tamm Alexander R.,
Ruf Tobias F.,
Kreidel Felix,
Hahad Omar,
Ahoopai Majid,
Hobohm Lukas,
BeirasFernandez Andres,
Kornberger Angela,
Schulz Eberhard,
Münzel Thomas,
Bardeleben Ralph Stephan
Publication year - 2021
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.29068
Subject(s) - medicine , mitral regurgitation , retrospective cohort study , mitral valve repair , mitraclip , surgery , mitral valve , etiology , survival analysis , cardiology
Objectives Transcatheter mitral valve repair (TMVR) by edge‐to‐edge therapy is an established treatment for severe mitral valve regurgitation (MR). Background Symptomatic and prognostic benefit in functional MR has been shown recently; nevertheless, data on long‐term outcomes are sparse. Methods and results We analyzed survival of patients treated with isolated edge‐to‐edge repair from June 2010 to March 2018 (primarily combined edge‐to‐edge repair with other mitral valve interventions was excluded) in a retrospective monocentric study. Overall, 627 consecutive patients (47.0% females, 78.6 years in mean) were included. Leading etiology was functional MR (57.4%). Follow‐up regarding survival was available in 97.0%. While 97.6% were discharged alive, 75.7% were alive after a 1‐year, 54.5% after 3‐year, 37.6% after 5‐year and 21.7% after 7‐year follow‐up. Higher logistic Euroscores and comorbidities such as COPD and renal insufficiency were associated with higher in‐hospital and 1‐year mortality. Importantly, in‐hospital survival increased over the years. Conclusions With the present study we established high survival rates at discharge and after 1 year of patients treated with TMVR. This goes along with high implantation numbers, increased interventional experience and a better in‐hospital survival over the years. Long‐term mortality in turn was substantially influenced by comorbidities.