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Characteristics of non‐culprit plaques in acute coronary syndrome patients with calcified plaque at the culprit lesion
Author(s) -
Kim Hyung Oh,
Kim Chong Jin,
Cho JinMan,
Soeda Tsunenari,
Kurihara Osamu,
Russo Michele,
Araki Makoto,
Lee Hang,
Minami Yoshiyasu,
Jang IkKyung
Publication year - 2021
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.29005
Subject(s) - medicine , culprit , acute coronary syndrome , fibrous cap , cardiology , vulnerable plaque , lesion , calcium , surgery , myocardial infarction
Objectives To investigate the non‐culprit plaques (NCPs) characteristics in acute coronary syndrome (ACS) patients with calcified plaques (CP). Background Recently, a new in vivo classification of calcified culprit plaques in patients with ACS was proposed. Characteristics of NCPs in this group of patients are unknown. Methods A total of 692 NCPs from 492 ACS patients were retrospectively compared based on the culprit plaque phenotype: 71 from CP patients, 383 from plaque rupture (PR) patients, 238 from plaque erosion (PE) patients. Results NCPs of CP patients had greater maximal calcium thickness, wider calcium arc, longer calcium length, and greater calcium index, compared to PR or PE patients (CP vs. PR: all p < .001, CP vs. PE: all p < .001). Thin‐cap fibroatheroma was less prevalent ( p = .023), fibrous cap was thicker ( p = .035), and mean lipid arc was narrower in CP than in PR ( p < .001). Conclusions In conclusion, NCPs of CP patients had greater calcium burden and less vulnerability. This information may help to better understand the underlying mechanisms of ACS and to develop strategy for tailored management.