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Impact of aortic angle on transcatheter aortic valve implantation outcome with Evolut‐R , Portico, and Acurate‐NEO
Author(s) -
Gorla Riccardo,
De Marco Federico,
Garatti Andrea,
Bianchi Giovanni,
Popolo Rubbio Antonio,
Acerbi Elena,
Casenghi Matteo,
Spagnolo Pietro,
Brambilla Nedy,
Testa Luca,
Agnifili Mauro L.,
Tusa Maurizio,
Bedogni Francesco
Publication year - 2021
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.28957
Subject(s) - medicine , cardiology , stenosis , cardiac skeleton , aortic valve , aortic valve stenosis , bicuspid aortic valve , population , aortic valve replacement , environmental health
Objectives To investigate paravalvular leak (PVL) and devices success rates according to aortic angle (AA) in patients undergoing transcatheter aortic valve implantation (TAVI) with three new‐generation self‐expanding devices. Background The impact of aortic angle (AA) on TAVI device success and PVL rates is controversial. Methods This retrospective study included 392 patients submitted to TAVI for severe aortic stenosis with Portico, Evolut‐R and Acurate‐NEO, and available AA measurements at computed tomography (CT) angiography. AA was calculated from the implantation projection and was defined as the angle between the plane of aortic annulus and an ideal horizontal plane. Aorta was defined horizontal if AA>57° (75th percentile). Results In the horizontal group, the rates of moderate/severe PVL was higher in the Evolut‐R group (20.8%), which was also characterized by a lower implant compared to that of Acurate‐NEO, whereas device success was comparable among the three devices. AA was a significant predictor of moderate/severe PVLs (AUC 0.72, p = .002) only in the Evolut‐R population. On multivariate analysis, calcium volume 850HU, bicuspid aortic valve, and implantation depth at the level of left coronary cusp were independent predictors of moderate/severe PVL. On univariate analysis in the horizontal aorta population, implantation depth was confirmed among the most significant predictors of moderate/severe PVL. Conclusions Despite comparable device success rates, horizontal aorta represented a technical challenge only in the Evolut‐R subgroup, which showed higher rates of moderate/severe PVL than Portico and Acurate‐NEO, and was associated with a low implant.