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Effect of cutting balloon after rotational atherectomy in severely calcified coronary artery lesions as assessed by optical coherence tomography
Author(s) -
Amemiya Kisaki,
Yamamoto Myong Hwa,
Maehara Akiko,
Oyama Yuji,
Igawa Wataru,
Ono Morio,
Kido Takehiko,
Ebara Seitarou,
Okabe Toshitaka,
Yamashita Kennosuke,
Hoshimoto Koichi,
Saito Shigeo,
Yakushiji Tadayuki,
Isomura Naoei,
Araki Hiroshi,
Mintz Gary S.,
Ochiai Masahiko
Publication year - 2019
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.28278
Subject(s) - medicine , balloon , stent , confidence interval , angioplasty , cutting balloon , atherectomy , calcium , cardiology , radiology , nuclear medicine , surgery , restenosis
Objectives Using optical coherence tomography (OCT), we evaluated the effect of a cutting balloon (CB) compared with a conventional balloon after rotational atherectomy (RA) and before stenting in severely calcified coronary lesions. Background A CB is designed to create discrete incisions to facilitate fracture of severely calcified plaque. Methods OCT was performed preintervention (if possible), post‐RA, and poststent implantation. RA modification of calcium was defined as a polished, concave, round‐shaped surface. Calcium fracture was defined as a break in the calcium plate. The effects of calcium modification and stent expansion between CB ( n = 18) versus conventional balloon ( n = 23) following RA were compared. Results Median patient age was 72 years with 24% on hemodialysis. The amount of calcium and the length of RA modification were comparable between the CB and conventional balloon groups. Final poststent OCT showed that the number and thickness of calcium fracture were greater after CB versus conventional balloon, resulting better stent expansion (78.9% [IQR: 72.4–88.1] vs. 66.7% [IQR: 55.0–76.7], p < 0.01). In the multivariable model, after adjusting for the amount of calcium, CB use was an independent predictor of the presence of calcium fracture (odds ratio 30.0; 95% confidence interval 2.7–994.1, p = 0.004) and an independent predictor for greater stent expansion (regression coefficient 7.4; 95% confidence interval 0.5–14.3, p = 0.04). Conclusion In severely calcified lesions calcium fracture was more often associated with RA followed by CB compared with RA followed by conventional balloon predilation before stenting. CB use was also a determinant of greater stent expansion.