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Intracoronary recombinant tissue plasminogen activator in an infant with hypoplastic left heart syndrome and complete left main coronary artery thrombosis
Author(s) -
Mohammad Nijres Bassel,
Huntington John H.,
Baliulis Giedrius,
Vettukattil Joseph J.
Publication year - 2019
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.28092
Subject(s) - medicine , hypoplastic left heart syndrome , cardiology , thrombosis , ventricle , left coronary artery , artery , coronary thrombosis , recombinant tissue plasminogen activator , acute coronary syndrome , myocardial infarction , heart disease , ischemia , ischemic stroke , modified rankin scale
An infant with hypoplastic left heart syndrome (HLHS) presented with complete heart block and severe myocardial dysfunction requiring ECMO support due to complete left main coronary artery (LMCA) thrombosis. Current guidelines for managing coronary artery thrombosis in infants with single ventricle physiology are inadequate. We describe successful LMCA and branch recanalization via intra coronary infusion of recombinant tissue plasminogen activator and discuss management of acute coronary thrombosis in children with single ventricle physiology.