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Safety and efficacy of self‐apposing Stentys drug‐eluting stent in left main coronary artery PCI: Multicentre LM‐STENTYS registry
Author(s) -
Wańha Wojciech,
Mielczarek Maksymilian,
Smolka Grzegorz,
Roleder Tomasz,
Jaguszewski Miłosz,
Ciećwierz Dariusz,
Tomasiewicz Bru,
Kubler Piotr,
Gorol Jarosław,
Chmielecki Michał,
Bartuś Stanisław,
Navarese Eliano Pio,
Kasprzak Michał,
Sukiennik Adam,
Kubica Jacek,
Lekston Andrzej,
Hawranek Michał,
Reczuch Krzysztof,
Gruchała Marcin,
Ochała Andrzej,
Wojakowski Wojciech
Publication year - 2019
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.27876
Subject(s) - medicine , conventional pci , percutaneous coronary intervention , myocardial infarction , clinical endpoint , cardiology , unstable angina , acute coronary syndrome , stroke (engine) , stent , angina , surgery , clinical trial , mechanical engineering , engineering
Background There is a paucity of data on left main (LM) percutaneous coronary intervention (PCI) therapy with dedicated DES platforms. The LM‐STENTYS is a multicenter registry aimed at evaluating clinical outcome after PCI of LM performed with a self‐apposing Stentys DES implantation. Methods The registry consists of 175 consecutive patients treated with Stentys DES implanted to LM. The primary endpoint was the composite of major adverse cardiac and cerebral events (MACCE) defined as cardiac death, myocardial infarction (MI), target lesion revascularization (TLR), and stroke assessed after 1 year. The secondary endpoint was stent thrombosis (ST) at 1 year. Results The median age was 69 years (IQR, 62–78 years). Acute coronary syndrome (ACS) was the presenting diagnosis in 117 (66.9%) patients [74 (63.2%) unstable angina, 31 (26.5%) NSTEMI, 12 (10.3%) STEMI] and stable angina (SA) was present in 58 (33.1%) patients. The median SYNTAX score was 23.0 (IQR, 18.7–32.2) in the SA group and 25.0 (IQR, 20.0–30.7) in the ACS group. During 1‐year follow‐up in the SA group two (3.4%) MACCE occurred, both of them were cardiac deaths. In ACS patients there were 19 (16.2%) MACCE [9 (7.7%) cardiac deaths, 11 (9.4%) MIs, 11(9.4%) TLR, 1(0.9%) stroke]. Altogether, three (1.7%) cases of acute ST were noted, all of them in ACS subset. Conclusion LM PCI using self‐apposing Stentys DES showed favorable clinical outcomes at 1‐year in patients with SA. Events of ST in the ACS group warrant further research.