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Infective endocarditis following transcatheter edge‐to‐edge mitral valve repair: A systematic review
Author(s) -
Asmarats Lluis,
RodriguezGabella Tania,
Chamandi Chekrallah,
Bernier Mathieu,
Beaudoin Jonathan,
O'Connor Kim,
Dumont Eric,
Dagenais François,
Paradis JeanMichel,
RodésCabau Josep
Publication year - 2018
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.27632
Subject(s) - medicine , mitral regurgitation , mitral valve repair , infective endocarditis , endocarditis , complication , mitral valve , surgery , mitraclip , mitral valve replacement , cardiology , cochrane library , randomized controlled trial
Objectives To assess the clinical characteristics, management, and outcomes of patients diagnosed with infective endocarditis (IE) after edge‐to‐edge mitral valve repair with the MitraClip device. Background Transcatheter edge‐to‐edge mitral valve repair has emerged as an alternative to surgery in high‐risk patients. However, few data exist on IE following transcatheter mitral procedures. Methods Four electronic databases (PubMed, Google Scholar, Embase, and Cochrane Library) were searched for original published studies on IE after edge‐to‐edge transcatheter mitral valve repair from 2003 to 2017. Results A total of 10 publications describing 12 patients with definitive IE (median age 76 years, 55% men) were found. The mean logistic EuroSCORE/EuroSCORE II were 41% and 45%, respectively. The IE episode occurred early (within 12 months post‐procedure) in nine patients (75%; within the first month in five patients). Staphylococcus aureus was the most frequent (60%) causal microorganism, and severe mitral regurgitation was present in all cases but one. Surgical mitral valve replacement (SMVR) was performed in most (67%) patients, and the mortality associated with the IE episode was high (42%). Conclusions IE following transcatheter edge‐to‐edge mitral valve repair is a rare but life‐threatening complication, usually necessitating SMVR despite the high‐risk profile of the patients. These results highlight the importance of adequate preventive measures and a prompt diagnosis and treatment of this serious complication.