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Periprocedural transfusion in patients undergoing transfemoral transcatheter aortic valve implantation
Author(s) -
Mayr N Patrick,
Wiesner Gunther,
Hapfelmeier Alexander,
van der Starre Pieter,
Husser Oliver,
Bleiziffer Sabine,
Schunkert Heribert,
Lange Rüdiger,
TassaniPrell Peter,
Martin Klaus
Publication year - 2018
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.27382
Subject(s) - medicine , pericardial effusion , blood transfusion , cardiology , anemia , pleural effusion , adverse effect , surgery
Objectives The aim of this investigation was to identify patient's characteristics and periprocedural variables related to periprocedural transfusion in transfemoral Transcatheter Aortic Valve Implantation (tf‐TAVI). Background Transfusion of allogenic red‐blood cells (RBC) in tf‐TAVI and the number of transfused units has been linked to an increased 30‐day mortality. In line with the trend of minimization and cost‐effectiveness, transfusion should be avoided, wherever possible. Methods Between 2007 and 2015, 1,734 procedures were analyzed from our prospective registry for RBC‐transfusion. Multiple logistic regression analysis was used to identify the dependent variables. Results Transfusion was considered necessary in 14% ( n = 243) of the patients. Female gender (OR [95% CI]) (1.680 [1.014‐2.783]) and preprocedural moderate (7.594 [4.404‐13.095]) and severe anemia (8.202 [0.900‐74.752]) according to WHO were the most important preprocedural variables. Periprocedural, pericardial effusion (12.109 [3.753‐39.063]), emergency extracorporeal circulation (54.5288 [6.178‐481.259]) and major vascular injury (2.647 [1.412‐4.962]) were related to transfusion. The same applies to moderate (4.255 [1.859‐9.740]) and severe anemia (31.567 [8.560‐116.416]) as well as periprocedural experience (0.072 [0.035‐0.149] – 0.141[0.079‐0.251], P < 0.001) Conclusion Procedural experience, serious adverse events, low pre‐ and periprocedural Hb levels and female gender were the main variables relating to transfusion. Even in experienced high‐volume centers, transfusion is still necessary in a considerable number of patients.