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Initial clinical experience with the Medtronic Micro Vascular Plug™ in transcatheter occlusion of PDAs in extremely premature infants
Author(s) -
Sathanandam Shyam,
Justino Henri,
Waller B. Rush,
Radtke Wolfgang,
Qureshi Athar M.
Publication year - 2017
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.26878
Subject(s) - medicine , occlusion , embolization , ductus arteriosus , fluoroscopy , surgery , gestational age , shunt (medical) , vascular occlusion , radiology , pregnancy , genetics , biology
Objectives To describe the early multicenter, clinical experience with the Medtronic Micro Vascular Plug™ (MVP) for the occlusion of patent ductus arteriosus (PDA) in premature infants. Background The MVP is a large diameter plug that can be delivered through a microcatheter for occlusion of abnormal blood vessels. Methods A Retrospective review of PDA embolization procedures performed in two centers using the MVP was performed. Results Fifteen premature infants underwent attempted PDA occlusion using the MVP. The gestational age and birth weight were 25.6 ± 2.5 weeks and 735 ± 251 g, respectively. The median weight and age at the time of the procedure were 1,210 g (700–3,500 g) and 4.5 weeks (2–12 weeks), respectively. Median procedure and fluoroscopy times were 45 and 6.5 min, respectively. The median radiation and contrast doses were 19.7 mGy and 2.4 mL/kg, respectively. Antegrade occlusion was successfully achieved in 13 patients <2 kg with only femoral venous access aided by echo guidance. The two patients >2 kg had arterial access and attempted retrograde occlusion; one of which was unsuccessful due to the PDA being short and wide. Complete closure was observed in 13 of 14 successful procedures (93%), with one patient having a small residual shunt that was not seen on follow‐up. There were no complications related to the procedure or noted during follow‐up (Median 11 months). Conclusions The MVP is a new, large‐diameter vascular embolization device that may be useful for the occlusion of PDA in extremely small, premature infants. © 2016 Wiley Periodicals, Inc.