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Orbital atherectomy for severely calcified lesions: More dissections in women but similar 30‐day outcomes to men
Author(s) -
Chandrasekhar Jaya,
Mehran Roxana
Publication year - 2016
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.26492
Subject(s) - medicine , conventional pci , percutaneous coronary intervention , atherectomy , calcification , lesion , balloon , revascularization , surgery , angioplasty , radiology , stent , cardiology , restenosis , myocardial infarction
Key Points Calcified lesions are associated with lower rates of successful percutaneous coronary intervention (PCI), greater stent thrombosis, and increased target vessel revascularization. Women undergoing PCI are more often older than men and likely to present with severe lesion calcification. The ORBIT II study, for the first time compares the effect of the orbital atherectomy system (OAS) in men and women undergoing PCI for severely calcified lesions. Although the adjusted risk of severe dissections was higher in women, the incidence of in‐hospital and 30‐day outcomes was similar to men. Randomized comparisons of the OAS with rotational atherectomy and with stenting without atherectomy are needed to further elucidate sex‐based differences in calcified lesion PCI.