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Development of a novel hybrid strategy for transcatheter pulmonary valve placement in patients following transannular patch repair of tetralogy of fallot
Author(s) -
Phillips Alistair B. M.,
Nevin Phillip,
Shah Avni,
Olshove Vincent,
Garg Ruchira,
Zahn Evan M.
Publication year - 2016
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.26315
Subject(s) - medicine , tetralogy of fallot , ventricular outflow tract , pulmonary valve , cardiology , stent , population , pulmonary valve insufficiency , surgery , pulmonary regurgitation , heart disease , environmental health
Background Transcatheter pulmonary valve replacement (tPVR) is an accepted therapy for treatment of dysfunctional right ventricular outflow tract (RVOT) conduits. At present, the majority of Fallot patients who undergo transannular patch (TAP) repair are not candidates for tPVR due to the large irregular nature of their RVOT. Herein, we describe a novel approach to assessing the RVOT in this group, which may then be used to design, test, and carry out hybrid RVOT modification and transcatheter valve implantation in this population. Methods A retrospective analysis of TAP patients who underwent 3D modeling of the RVOT which was then used to develop individualized hybrid procedures designed to modify the RVOT, thereby rendering patients suitable for transcatheter valve implantation. Results Eight consecutive patients underwent 3D RVOT modeling followed by hybrid implantation of a transcatheter valve via a perventricular approach. A landing zone stent was placed in all and four required additional intravascular geometric remodeling of the RVOT prior to valve implant. Transcatheter valves were successfully implanted in all. There were no instances of valve malposition, embolization, or death. There was one minor procedural complication. No patient had more than trivial pulmonary regurgitation at follow‐up. Conclusions Using a hybrid approach to remodel the RVOT in TAP patients supported by preprocedural 3D‐model planning allows for successful tPVR implantation in this population. A larger cohort and longer follow‐up will be needed to determine the ultimate utility of this approach. © 2015 Wiley Periodicals, Inc.