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Cardiac computed tomography assessment of the near term impact of percutaneous ventricular restoration therapy (parachute ® ) on mitral valve geometry
Author(s) -
Tam Chor Cheung,
Fares Anas,
Alaiti Amer,
Shaikh Kashif,
Ince Hüseyin,
Erglis Andrejs,
Bezerra Hiram G.,
Abraham William T.,
Costa Marco A.,
Attizzani Guilherme F.
Publication year - 2016
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.26291
Subject(s) - medicine , percutaneous , cardiology , myocardial infarction , mitral valve , heart failure , stroke volume , ejection fraction , nuclear medicine
Objectives The aim of current study is to assess the near term impact of percutaneous ventricular restoration therapy (PVR), Parachute ® on mitral valve (MV) geometry by cardiac computed tomography (CCT). Background Recent data demonstrates the feasibility of PVR for treatment of post anterior myocardial infarction (MI) heart failure. Little is known, however, about the interaction of the device and left ventricular structures, particularly the MV apparatus. Methods This is a retrospective Core Laboratory analysis of Parachute Trials’ CCT data. Patients with paired (before and after Parachute implant) CCT acquisitions were included into analysis. MV geometric parameters were measured. Results Thirty‐three patients were included in the analysis. The mean time of follow‐up CCT post procedure was 188 ± 52 days. There were significant reduction in tenting height (A1P1: −1.70 ± 1.89 mm, −17.40 ± 20.20%; A2P2: −1.43 ± 1.89 mm, −12.10 ± 15.00%; A3P3: −1.54 ± 1.58 mm, −15.50 ± 15.20%, P < 0.001), tenting volume (−0.93 ± 0.60 mm3, −22.00 ± 11.40%, P < 0.001), systolic interpapillary muscle distance (−2.22 ± 2.11 mm, −7.51 ± 7.23%, P < 0.001) and diastolic interpapillary muscle distance (−3.14 ± 2.20 mm, −8.46 ± 5.73%, P < 0.001) post PVR. Conclusions In post anterior MI heart failure patients, PVR has favorable near term impact on MV geometry as assessed by CCT. © 2015 Wiley Periodicals, Inc.