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Trans‐subclavian versus transapical access for transcatheter aortic valve implantation: A multicenter study
Author(s) -
Ciuca Cristina,
Tarantini Giuseppe,
Latib Azeem,
Gasparetto Valeria,
Savini Carlo,
Di Eusanio Marco,
Napodano Massimo,
Maisano Francesco,
Gerosa Gino,
Sticchi Alessandro,
Marzocchi Antonio,
Alfieri Ottavio,
Colombo Antonio,
Saia Francesco
Publication year - 2015
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.26012
Subject(s) - medicine , myocardial infarction , cardiology , stroke (engine) , sepsis , aortic valve , surgery , mechanical engineering , engineering
Objectives To compare the outcomes of trans‐subclavian (TS) and transapical (TA) access for transcatheter aortic valve implantation (TAVI). Background A considerable proportion of patients undergoing TAVI are not eligible for transfemoral approach. To date, there are few data to guide the choice between alternative vascular access routes. Methods Among 874 consecutive patients who underwent TAVI, 202 procedures were performed through TA ( n = 142, 70.3%) or TS ( n = 60, 29.7%) access. Medtronic Corevalve (CV, Medtronic, Minneapolis, MN) was implanted in 17.3% of the patients, the Edwards‐Sapien (ES, Edwards Lifesciences Inc., Irvine, CA) in 81.2% and other prostheses in 0.1%. In‐hospital and long‐term outcome were assessed using the Valve Academic Research Consortium (VARC)‐2 definitions. Results Mean age was 82 ± 6 years, STS score 9.3 ± 7.9%. The 2 groups showed a relevant imbalance in baseline characteristics. In hospital mortality was 6.4% (1.7% TS vs. 8.4% TA, P = 0.06), stroke 2.0%, acute myocardial infarction 1.0%, acute kidney injury 39.4%, sepsis 4.0% with no significant differences between groups, while bleeding was more frequent in TA patients (53.5% vs. 11.7% TS, P < 0.001). One‐ and 2‐year survival was 85.2% and 73.2% in TS patients, and 83.9% and 74.9% in TA patients ( P = ns for both). Access site was not an independent predictor of mortality at multivariable analysis. Conclusion Transapical compared with trans‐subclavian access for TAVI was associated with a nonsignificant trend to increased periprocedural events. However, 1‐ and 2‐year survival appears similar. © 2015 Wiley Periodicals, Inc.