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Fractional Flow Reserve for the Evaluation of Coronary Stenoses
Author(s) -
Jeremias Allen,
Stone Gregg W.
Publication year - 2015
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.25851
Subject(s) - fractional flow reserve , medicine , coronary angiography , revascularization , cardiology , reactive hyperemia , clinical trial , cath lab , radiology , conventional pci , blood flow , myocardial infarction
Key Points To guide the decision‐making process for coronary revascularization in the cath lab, FFR has been proven to enhance patient outcomes and reduce costs compared with angiography alone However, FFR is prone to artifacts, may yield inaccurate results, and is under‐utilized in practice, in part because of the requisite use of hyperemia which is cumbersome and produces variable clinical responses Interest is growing in resting indices such as Pd/Pa and iFR that do not require hyperemia and therefore simplify the procedure and allow for multiple pre‐ and post‐procedural lesion assessments Two large randomized trials are ongoing comparing clinical outcomes with iFR vs. FFR that may determine the future adoption of resting coronary indices