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A prospective multicenter registry of 0.010‐inch guidewire and compatible system for chronic total occlusion: The PIKACHU registry
Author(s) -
Matsukage Takashi,
Masutani Motomaru,
Yoshimachi Fuminobu,
Takahashi Akihiko,
Katsuki Takaaki,
Saito Shigeru,
Terai Hidenobu,
Katahira Yoshiaki,
Uehara Yoshiki,
Tohara Satoru,
Ohba Yurika,
Shinohara Shoichi,
Asano Hiroshi,
Matsumura Toshiyuki,
Hata Tetsuya,
Ikari Yuji
Publication year - 2010
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.22434
Subject(s) - medicine , surgery , balloon , occlusion , conventional pci , catheter , prospective cohort study , mace , balloon catheter , target lesion , lesion , radiology , myocardial infarction , percutaneous coronary intervention
Objectives : The aim of this study was to evaluate the safety and effectiveness of a 0.010‐inch guidewire and a balloon catheter for treatment of chronic total occlusion (CTO). Background : Pathological studies have shown that 60–70% of CTO lesions have microchannels of sizes equal to or less than 0.010 inch. Methods : The PIKACHU registry is a prospective, multicenter registry study. A 0.010‐inch guidewire had to be used as the first guidewire to attempt to pass the CTO lesion. The primary endpoint was device success using a 0.010 system. Results : A total of 141 patients with 141 lesions were enrolled. The median duration of occlusion was 9 months (range 3–156). Average guiding catheter size was 5.8 ± 0.7 Fr. and TRI was 76.6 %. CTOs were mostly between 10–20 mm long, observed in 53 occlusions. There were 107 lesions (75.9%) with bending of more than 45 degrees. Calcification was seen in 91 lesions (64.5%). A 0.010‐inch guidewire was successfully passed through in 97 of 141 lesions (68.8%). A 0.010‐inch guidewire compatible balloon catheter was passed in 87 of the 97 lesions (88.7%) and final PCI success was achieved in all the cases. The overall clinical success rate was 87.9% (124/141). No MACE or bleeding complications were observed. Conclusion : The PIKACHU registry data suggest that the 0.010‐inch system is safe and practicable for treatment of CTO lesions. © 2010 Wiley‐Liss, Inc.